primerarray jak stat signaling pathway human qpcr array Search Results


jak stat inhibition  (Selleck Chemicals)
96
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jak stat signaling pathway inhibitor linderalactone  (MedChemExpress)
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MedChemExpress jak stat signaling pathway inhibitor linderalactone
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jak stat pathway  (MedChemExpress)
99
MedChemExpress jak stat pathway
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Jak Stat Pathway, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rabbit anti socs1  (Boster Bio)
93
Boster Bio rabbit anti socs1
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
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ruxolitinib  (Selleck Chemicals)
96
Selleck Chemicals ruxolitinib
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
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molecule jak stat inhibitor  (Gilead Sciences)
99
Gilead Sciences molecule jak stat inhibitor
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Molecule Jak Stat Inhibitor, supplied by Gilead Sciences, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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jak stat inhibitor ruxolitinib  (MedChemExpress)
97
MedChemExpress jak stat inhibitor ruxolitinib
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Jak Stat Inhibitor Ruxolitinib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human jak/stat oligo gearray  (SuperArray Bioscience Corporation)
90
SuperArray Bioscience Corporation human jak/stat oligo gearray
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Human Jak/Stat Oligo Gearray, supplied by SuperArray Bioscience Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human jak/stat signaling primer library  (Real Time Primers)
90
Real Time Primers human jak/stat signaling primer library
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Human Jak/Stat Signaling Primer Library, supplied by Real Time Primers, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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socs  (Cell Signaling Technology Inc)
91
Cell Signaling Technology Inc socs
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Socs, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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jak stat inhibitor hy 15315  (MedChemExpress)
96
MedChemExpress jak stat inhibitor hy 15315
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Jak Stat Inhibitor Hy 15315, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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erlotinib marketed for non–small cell lung cancer (nsclc)  (OSI Pharmaceuticals)
90
OSI Pharmaceuticals erlotinib marketed for non–small cell lung cancer (nsclc)
Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription <t>(JAK/STAT)</t> pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group
Erlotinib Marketed For Non–Small Cell Lung Cancer (Nsclc), supplied by OSI Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group

Journal: BMC Musculoskeletal Disorders

Article Title: Knockdown of CLEC4D alleviates myoblast dysfunction and inflammation in sarcopenia by inhibiting the JAK/STAT pathway

doi: 10.1186/s12891-025-09085-x

Figure Lengend Snippet: Screening of potential downstream pathways of CLEC4D in sarcopenia. ( A ) Venn diagram showing the intersection of CLEC4D co-expressed genes with genes related to sarcopenia. ( B ) KEGG pathway enrichment analysis of common DEGs. ( C ) Western blot detection of proteins involved in the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group

Article Snippet: Additionally, the JAK/STAT pathway was activated by treating cells with the JAK/STAT activator RO8191 (2 μM; MedChemExpress, New Jersey, USA) for 24 h.

Techniques: Western Blot, Control

Silencing CLEC4D attenuates D-gal-induced myoblast dysfunction and inflammation via inhibiting the JAK/STAT pathway. ( A ) CCK-8 assay measuring cell viability. ( B ) Flow cytometry analysis of apoptosis levels. ( C ) SA-β-gal staining (Magnification: 200×, Scale bar: 100 μm). ( D ) RT-qPCR analysis of the mRNA expression of myogenic markers. ( E ) RT-qPCR analysis of the mRNA expression of muscle atrophy markers. ( F ) Western blot detection of proteins related to myoblast differentiation. ( G ) Western blot analysis of muscle atrophy marker expression. ( H ) ELISA for detecting inflammatory factors in cells. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group, $$ P < 0.01 vs. D-gal + LV-shCLEC4D group

Journal: BMC Musculoskeletal Disorders

Article Title: Knockdown of CLEC4D alleviates myoblast dysfunction and inflammation in sarcopenia by inhibiting the JAK/STAT pathway

doi: 10.1186/s12891-025-09085-x

Figure Lengend Snippet: Silencing CLEC4D attenuates D-gal-induced myoblast dysfunction and inflammation via inhibiting the JAK/STAT pathway. ( A ) CCK-8 assay measuring cell viability. ( B ) Flow cytometry analysis of apoptosis levels. ( C ) SA-β-gal staining (Magnification: 200×, Scale bar: 100 μm). ( D ) RT-qPCR analysis of the mRNA expression of myogenic markers. ( E ) RT-qPCR analysis of the mRNA expression of muscle atrophy markers. ( F ) Western blot detection of proteins related to myoblast differentiation. ( G ) Western blot analysis of muscle atrophy marker expression. ( H ) ELISA for detecting inflammatory factors in cells. ** P < 0.01 vs. Control group, ## P < 0.01 vs. D-gal + LV-shNC group, $$ P < 0.01 vs. D-gal + LV-shCLEC4D group

Article Snippet: Additionally, the JAK/STAT pathway was activated by treating cells with the JAK/STAT activator RO8191 (2 μM; MedChemExpress, New Jersey, USA) for 24 h.

Techniques: CCK-8 Assay, Flow Cytometry, Staining, Quantitative RT-PCR, Expressing, Western Blot, Marker, Enzyme-linked Immunosorbent Assay, Control